Pyometra Totally Explained

Everything about Pyometra totally explained

Pyometra is a disease of the uterus most commonly seen in female dogs, but also seen in queens (female cats), rabbits, ferrets, rats and guinea pigs. Pyometra is an important disease to be aware of for any dog owner because of the sudden nature of the disease and the deadly consequences if left untreated. It has been compared to acute appendicitis in humans, because both are essentially empyemas within an abdominal organ.

Cause of pyometra

Pyometra is a result of hormonal and structural changes in the uterus lining. This can happen at any age, whether she's bred or not, and whether it's her 1st or 10th heat (although it becomes more common as the dog gets older). The main risk period for a female is for eight weeks after her peak standing heat (or estrus cycle) has ended. Normally during this period, the cervix, which was open during her heat, begins to close, and the inner lining begins to adapt back to normal. However, cystic hyperplasia of the endometrium (inner lining of the uterus) - known as cystic endometrial hyperplasia (CEH) - may occur at this time for some animals, as an inappropriate response to progesterone.
Under these circumstances, bacteria (especially E. coli) that have migrated from the vagina into the uterus find the environment favorable to growth, especially since progesterone also causes mucus secretion, closes the cervix (preventing uterine drainage), and decreases uterine contractility. The condition of the cervix is a major factor in the severity of the condition. ť * If the cervix is open, the infected material can leave the body, and this is far easier and safer to treat. This is known as open pyometra.

* If the cervix is fully closed, there's no discharge from the vulva, and like in appendicitis, the uterus may rupture and pus escapes into the abdomen, causing peritonitis and possible rapid death. This is known as closed pyometra.

Hormonal influences and mis-mating shots

Bitches that have received estradiol as a mismating shot (abortifacient) in diestrus are at risk for more severe disease because estrogen increases the number of progesterone receptors in the endometrium. 25 percent of bitches receiving estradiol in diestrus develop pyometra. Pyometra is less common in female cats because progesterone is only released by the ovaries after mating.

Symptoms

The most obvious symptom of open pyometra is a discharge of pus from the vulva in a bitch that has recently been in heat. However, symptoms of closed pyometra are less obvious. Symptoms of both types include vomiting, loss of appetite, depression, and increased drinking and urinating. Fever is seen in less than a third of bitches with pyometra. This treatment should only be used with an open pyometra, because otherwise uterine rupture may occur. Less than 30 percent of bitches with closed pyometras are successfully treated in this way. Use of PGF₂-α should only be considered in bitches that are medically stable due to the length of time treatment takes. These bitches should be bred at the next estrus cycle and then spayed after parturition, because 70 percent will develop pyometra again in the next two years.

Stump Pyometra

Stump pyometra is a serious health condition that may occur in bitches that underwent Ovariohysterectomy (spaying). In this condition, the remaining stump of the resected Uterus becomes infected and filled with a purulent fluid. The symptoms are similar to those of true pyometra. The risk of this condition is significantly reduced if no uterine or ovarian tissue remains from the original ovariohysterectomy. Diagnosis of a stump pyometra may be challenging as pyometra is often discounted as a possibility if the bitch has been previously spayed.

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